L-arginine is one of many amino acids the body needs to function properly. Like other amino acids, L-arginine plays a role in building protein. The body can use the protein to help build muscle and rebuild tissue. As a result, researchers have investigated the effectiveness of L-arginine in the treatment of severe wounds and tissue waste in serious illnesses.
L-arginine is a chemical building block called “an amino acid.” It is obtained from the diet and is necessary for the body to make proteins. L-arginine is found in red meat, poultry, fish, and dairy products. It can also be made in a laboratory and used as medicine.
In addition to building protein, L-arginine releases nitric oxide in the blood.Nitric oxide acts to widen blood vessels in the blood stream, which may help aid certain circulatory conditions. A person’s body naturally produces L-arginine under normal circumstances. People also get additional L-arginine as part of their regular diet.
L-arginine is converted in the body into a chemical called nitric oxide. Nitric oxide causes blood vessels to open wider for improved blood flow. L-arginine also stimulates the release of growth hormone, insulin, and other substances in the body.
Specification of L-arginine
Test Items |
Standard |
Result |
Identification |
Infrared Absorption |
Complies |
Specific rotation |
between +26.3º to +27.7º |
+26.60° |
Loss on drying |
not more than 0.5% |
0.28% |
Residue on ignition |
not more than 0.3% |
0.15% |
Chloride |
not more than 0.05% |
<0.05% |
Sulfate |
not more than 0.03% |
<0.03% |
Iron |
not more than 0.003% |
<0.001% |
Heavy metals |
not more than 0.0015% |
<0.001% |
Chromatographic purity |
as per USP33 (By TLC) |
Complies |
Individual impurity |
≤0.5% |
<0.5% |
Total impurity |
≤2.0% |
<2.0% |
Organic volatile impurities |
Meets the requirements |
Complies |
Assay |
98.5% to 101.5% |
99.6% |
Characters: white or almost white, crystalline powder or colourless crystals, freely soluble in water |
Application & Benefits of L-arginine
L-arginine is used for heart and blood vessel conditions including congestive heart failure (CHF), chest pain, high blood pressure, and coronary artery disease. L-arginine is also used for recurrent pain in the legs due to blocked arteries (intermittent claudication), decreased mental capacity in the elderly (senile dementia), erectile dysfunction (ED), and male infertility.
Some people use L-arginine for preventing the common cold, improving kidney function after a kidney transplant, high blood pressure during pregnancy (pre-eclampsia), improving athletic performance, boosting the immune system, and preventing inflammation of the digestive tract in premature infants.
L-arginine is used in combination with a number of over-the-counter and prescription medications for various conditions. For example, L-arginine is used along with ibuprofen for migraine headaches; with conventional chemotherapy drugs for treating breast cancer; with other amino acids for treating weight loss in people with AIDS; and with fish oil and other supplements for reducing infections, improving wound healing, and shortening recovery time after surgery.
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