Eye-Drop Grade Hyaluronic Acid

Categories Health & Pharmaceuticals Ingredients, Hyaluronic Acid

Additional information

Product Name	Eye-Drop Grade Hyaluronic Acid / Sodium Hyaluronate
Appearance	White or almost white, highly hygroscopic powder
Chemical Formula	(C₁₄H₂₀NNaO₁₁)n
CAS Number	9067-32-7
Purity	≥ 95%
Solubility	Fully soluble in water, creating a clear and viscous solution
Molecular Weight	600~900 KDa, 1.2~1.6 MDa, 1.63~2.35 MDa
Main Functions	Superior Lubrication, Enhanced Hydration, High Biocompatibility, Optimal Viscosity Control, Protects Corneal Surface
Main Applications	Ophthalmic Formulations: Artificial Tears & Eye Drops, Contact Lens Solutions, Post-Surgical Eye Recovery, Therapeutic Eye Treatments : Pharmaceutical & Medical Uses: Wound Healing in Ophthalmology, Drug Delivery Systems

Product Details

Eye-Drop Grade Hyaluronic Acid – Premium Lubrication & Hydration for Ocular Health

Enhance eye comfort and hydration with GMP-certified, high-purity Hyaluronic Acid from Chibio Biotech!

1. What is Eye-Drop Grade Hyaluronic Acid?

Eye-Drop Grade Hyaluronic Acid (Sodium Hyaluronate) is a high-purity, medical-grade biopolymer used in ophthalmic solutions for eye lubrication, moisture retention, and corneal protection. It is widely applied in artificial tears, contact lens solutions, and post-surgical eye recovery formulations due to its exceptional viscoelasticity and biocompatibility.

At Chibio Biotech, our GMP-certified Hyaluronic Acid for eye drops is available in three molecular weight types, tailored to meet different viscosity and absorption needs.

2. Molecular Weight Classification & Benefits

Molecular Weight	Range (Da)	Key Benefits	Best Application
Low MW	600 – 900 kDa	Fast absorption, excellent spreadability	Daily-use artificial tears, contact lens solutions
Medium MW	1.2 – 1.6 MDa	Balanced hydration & viscosity, prolonged eye moisture	Multi-purpose lubricating eye drops, eye recovery solutions
High MW	1.65 – 2.35 MDa	Long-lasting hydration, strong protective film	Post-surgical eye care, severe dry eye treatment

🔹 Key Difference:

Low MW (600-900 kDa): Rapidly penetrates, providing instant hydration for mild dry eye relief.
Medium MW (1.2-1.6 MDa): Offers prolonged moisture retention, reducing evaporation.
High MW (1.65-2.35 MDa): Forms a thicker, protective layer, ideal for intensive eye hydration and post-surgical applications.

3. Technical Specifications

Feature	Specification
Product Name	Sodium Hyaluronate / Hyaluronic Acid (Eye-Drop Grade)
Chemical Formula	(C₁₄H₂₀NNaO₁₁)n
CAS Number	9067-32-7
Appearance	White or almost white, highly hygroscopic powder
Purity	≥ 95%
Solubility	Fully soluble in water, creating a clear and viscous solution
pH	5.0-8.5
Intrinsic Viscosity	1.2– 1.6 m3/kg (600-900 KDa) 2.0-2.6m3/kg (1.2-1.6 MDa) 2.7-3.6m3/kg (1.65-2.35 MDa)
Endotoxin Level	≤ 0.5 EU/mg
Microbial Limits	≤ 10 CFU/g
Heavy Metals	≤ 10 ppm
GMP Certification	✅ Yes

4. Key Benefits of Eye-Drop Grade Hyaluronic Acid

✅ Superior Lubrication – Forms a stable, long-lasting moisture barrier on the cornea.
✅ Enhanced Hydration – Prevents dryness, irritation, and tear evaporation.
✅ High Biocompatibility – Naturally occurring in the human eye, making it non-irritating.
✅ Optimal Viscosity Control – Adjustable molecular weight ensures customized absorption and retention.
✅ Protects Corneal Surface – Reduces friction and oxidative stress, aiding in eye healing.
✅ GMP Certified & Ultra-Pure – Meets strict pharmaceutical-grade safety standards.

5. Applications of Eye-Drop Grade Hyaluronic Acid

A. Ophthalmic Formulations

🔹 Artificial Tears & Eye Drops – Provides instant hydration for dry eyes.
🔹 Contact Lens Solutions – Enhances wearing comfort & lubrication.
🔹 Post-Surgical Eye Recovery – Supports healing after LASIK or cataract surgery.
🔹 Therapeutic Eye Treatments – Used in ophthalmic gels and medicated eye drops.

B. Pharmaceutical & Medical Uses

🔹 Wound Healing in Ophthalmology – Helps repair corneal damage.
🔹 Drug Delivery Systems – Improves bioavailability of eye medications.

6. Manufacturing Process (GMP-Certified Production)

1️⃣ Bacterial Fermentation Process

Microbial Fermentation – Produces ultra-pure HA under strict GMP conditions.
Filtration & Purification – Removes impurities and endotoxins, ensuring medical-grade quality.

2️⃣ Molecular Weight Adjustment

Optimized to 600-900 kDa, 1.2-1.6 MDa, and 1.65-2.35 MDa for different eye drop formulations.

3️⃣ Sterilization & Quality Testing

GMP-compliant sterilization ensures low endotoxin levels.
Stringent testing for purity, viscosity, and microbial limits.

4️⃣ Final Packaging & Distribution

Pharmaceutical-grade packaging to maintain HA stability and sterility.

7. Why Choose Chibio Biotech for Eye-Drop Grade Hyaluronic Acid?

🌍 GMP-Certified Production – Meets global pharmaceutical standards for eye care.
🔬 Advanced Purification Technology – Ensures ultra-low endotoxin levels for ophthalmic use.
📦 Custom Molecular Weights – Tailored HA solutions for different viscosity needs.
🌱 100% Biocompatible & Non-Irritating – Safe for long-term ocular use.
📈 Large-Scale Production & Reliable Supply – Stable and consistent bulk production.

8. Packaging & Storage

📦 Packaging: Customized according to pharmaceutical requirements
🌡 Storage: Store in a cool, dry place (2-10°C)
⏳ Shelf Life: Two years (Unopened packaging)