EDTA (Ethylenediaminetetraacetic Acid)

EDTA (Ethylenediaminetetraacetic Acid)

Additional information

Product Name

EDTA (Ethylenediaminetetraacetic acid)

Specifications

EDTA-ZnNa₂ (Zinc EDTA)
EDTA-MnNa₂ (Manganese EDTA)

CAS Number:

60-00-4 (free acid)

Main Functions

🧪 Chelating Agent
🌿 Micronutrient Stabilizer
🧼 Water Softener
💄 Preservative Synergist

Main Applications

Foliar sprays, fertigation systems, hydroponics, and feed additives.

Product Details

EDTA Chelated Micronutrients – EDTA-ZnNa₂ & EDTA-MnNa₂

Form: Water-soluble powder | Application Grade: Agricultural / Fertilizer / Feed Additive


1. Introduction

EDTA (Ethylenediaminetetraacetic acid) is a polyamino carboxylic acid and one of the most widely used chelating agents in industrial, agricultural, food, and pharmaceutical applications. It is capable of binding to metal ions like calcium, magnesium, iron, copper, zinc, and manganese, forming stable, water-soluble chelates.

It was first synthesized in the 1930s and has since become a critical ingredient for controlling metal ion reactivity, stability, and bioavailability in various formulations.

EDTA chelates are high-stability, water-soluble micronutrient sources that prevent precipitation or inactivation of metal ions in solution. Chibio Biotech supplies:

  • EDTA-ZnNa₂ (Zinc EDTA) – Zinc source for promoting enzyme activity, growth, and leaf chlorophyll synthesis.

  • EDTA-MnNa₂ (Manganese EDTA) – Manganese source for enhancing photosynthesis and nitrogen assimilation.

They are ideal for foliar sprays, fertigation systems, hydroponics, and feed additives.


2. Chemical Information of EDTA

  • Full Name: Ethylenediaminetetraacetic acid

  • Chemical Formula (free acid): C₁₀H₁₆N₂O₈

  • Molecular Weight: 292.24 g/mol (free acid)

  • CAS Number: 60-00-4 (free acid)

  • Structure: Comprises four carboxyl (–COOH) groups and two amine (–NH₂) groups capable of coordinating metal ions

Product EDTA-ZnNa₂ EDTA-MnNa₂
CAS No. 39208-16-7 15375-84-5
Molecular Formula C10H12N2O8ZnNa2 C10H12N2O8MnNa2
Appearance White powder Pink crystalline powder
Solubility Fully water-soluble Fully water-soluble
pH (1% solution) 6.0 – 7.0 (Tested: 6.74) 6.0 – 7.0 (Tested: 6.78)

3. Technical Specifications ​​

Parameter EDTA-ZnNa₂ EDTA-MnNa₂
Metal Content Zn: 14.5–15.5% (Result: 14.6%) Mn: 12.5–13.5% (Result: 12.6%)
Water Insoluble Matter ≤0.1% (0.05%) ≤0.1% (0.05%)
Appearance White powder Pink crystalline powder
Storage Cool, dry, sealed environment Same

4. Key Properties

Chelation Power: Binds strongly to metal ions through multiple coordination sites
pH-Dependent Stability: Effective over a wide pH range (pH 4–9)
Water-Soluble (in salt form): Solubility increases significantly as sodium salts (e.g., EDTA-Na₂, EDTA-Na₄)
Low Toxicity: Widely accepted in food, cosmetics, and personal care applications
Stable at Room Temperature: Long shelf-life in sealed packaging


5. Key Benefits &  Functional Roles

🧪 Chelating Agent

  • Sequesters metal ions to prevent precipitation, catalysis, or oxidation in formulations

  • Protects ingredients from metal-catalyzed degradation

🌿 Micronutrient Stabilizer

  • Used as metal carriers (Zn, Mn, Fe, Cu, Ca, etc.) in agriculture and hydroponics

  • Prevents metal lock-out in alkaline soils

🧼 Water Softener

  • Captures calcium and magnesium ions in detergents and cleaners

  • Improves foaming and cleaning efficiency in hard water

💄 Preservative Synergist

  • In cosmetics and food, it enhances antimicrobial performance by binding metal ions needed by microbes


🌿 EDTA-ZnNa₂

  • Stimulates enzyme systems and auxin production

  • Corrects zinc deficiency symptoms like leaf chlorosis and stunted growth

  • Enhances root development and pollen fertility

  • Suitable for all crops: cereals, vegetables, fruit trees

🌱 EDTA-MnNa₂

  • Boosts chlorophyll formation and photosynthesis

  • Aids nitrogen uptake and metabolism

  • Essential in enzyme activation and disease resistance

  • Effective in sandy or high-pH soils where Mn is less available


6. Common Forms & Derivatives

Form Description Use Case
EDTA (free acid) Low solubility Rare, mostly used in lab applications
EDTA-Na₂ (Disodium EDTA) Most common, moderate solubility Food, cosmetics, chelation therapy
EDTA-Na₄ (Tetrasodium EDTA) High solubility, alkaline Industrial cleaning, water treatment
EDTA-metal chelates (e.g., EDTA-ZnNa₂, EDTA-FeNa₂) Chelated micronutrients Agriculture, fertigation, feed

7. Regulatory & Safety

  • GRAS (Generally Recognized As Safe) by FDA for limited food uses

  • Allowed in cosmetics and personal care products in most regions

  • Safe for plant applications when used within recommended concentrations

  • Eco-toxicity is minimal when used correctly, but disposal must follow local regulations


8. Industries That Use EDTA

Industry Application
Agriculture Chelated micronutrients (EDTA-Zn, Mn, Fe, Cu, Ca) for foliar spray, soil, and hydroponics
Food & Beverage Antioxidant synergist, preservative enhancer
Pharmaceuticals Metal detoxification, stabilizer in formulations
Cosmetics Enhances preservative systems in lotions, creams, shampoos
Water Treatment Chelates metal ions to prevent scaling and corrosion
Detergents Improves efficiency by binding hardness ions

Applications & Recommended Dosage

Application EDTA-ZnNa₂ EDTA-MnNa₂
Foliar Spray 0.5–1.5 g/L 0.5–1.5 g/L
Soil Drench / Fertigation 2–4 kg/ha 2–4 kg/ha
Hydroponics 0.05–0.1 g/L 0.05–0.1 g/L
Feed Additive (trace mineral) As per formulation As per formulation

✅ Mixable with most NPK and micronutrient solutions
⚠ Avoid mixing with strong acids or incompatible salts


9. Production Flowchart (Applicable to Both EDTA-ZnNa₂ & EDTA-MnNa₂)

1. Raw Material Preparation

  • EDTA (ethylenediaminetetraacetic acid)

  • Zinc sulfate or manganese sulfate

  • Sodium hydroxide (NaOH)

2. Chelation Reaction

  • React EDTA with metal salt (ZnSO₄ or MnSO₄) under controlled pH and temperature

  • Addition of NaOH for neutralization and disodium salt formation

3. Purification

  • Removal of impurities and unreacted salts

  • Filtration to eliminate insoluble particles

4. Crystallization / Drying

  • Controlled drying to achieve desired particle size and moisture content

5. Grinding & Sieving

  • Uniform fine powder to meet 60–100 mesh standards

6. Quality Control (CCP)

  • Metal content assay

  • Solubility, pH, heavy metals, microbial tests

7. Final Packaging

  • Packed in moisture-proof bags or drums (25kg standard)

  • Custom OEM/private label available


10. Comparison: EDTA-ZnNa₂ vs EDTA-MnNa₂

🌿 EDTA-ZnNa₂ (EDTA Disodium Zinc Salt)

Primary Functions

  • Supplies chelated zinc, essential for auxin hormone synthesis, enzyme function, and leaf development

  • Corrects interveinal chlorosis, shortened internodes, and poor fruit set in zinc-deficient soils

Applications in Detail

  • Foliar Sprays: Rapid correction of zinc deficiency in citrus, grapes, vegetables, cotton

  • Soil/Fertigation: Ideal in calcareous or alkaline soils where zinc becomes unavailable

  • Hydroponics: Compatible with NPK solutions and maintains solubility over time

  • Feed Additives: Improves growth performance and immune function in livestock (trace mineral premix)

Typical Dosages

  • Foliar Spray: 0.5–1.5 g/L water

  • Soil/Fertigation: 2–4 kg/ha

  • Hydroponics: 0.05–0.1 g/L

  • Feed Formulations: Per regulatory or veterinary guidance


🌱 EDTA-MnNa₂ (EDTA Disodium Manganese Salt)

Primary Functions

  • Delivers chelated manganese, vital for chlorophyll formation, photosynthesis, and enzymatic activity

  • Prevents and corrects leaf interveinal yellowing, necrotic spots, and slow maturity

Applications in Detail

  • Foliar Sprays: Especially useful in citrus, soybeans, cereals, where Mn deficiency is common

  • Soil/Fertigation: Protects Mn from becoming insoluble in high pH or sandy soils

  • Hydroponics: Stable Mn source in mixed nutrient solutions

  • Feed Additives: Used for skeletal development and antioxidant activity in poultry and livestock

Typical Dosages

  • Foliar Spray: 0.5–1.5 g/L

  • Soil/Fertigation: 2–4 kg/ha

  • Hydroponics: 0.05–0.1 g/L

  • Feed Additives: Based on formulation needs or trace mineral limits


Comparison Table – EDTA-ZnNa₂ vs. EDTA-MnNa₂

Feature EDTA-ZnNa₂ EDTA-MnNa₂
Metal Content 14.6% Zn 12.6% Mn
Appearance White powder Pink crystalline
Main Function Enzyme activation, shoot growth, fertility Chlorophyll formation, N metabolism
Target Deficiencies Zinc deficiency (chlorosis, stunted growth) Manganese deficiency (interveinal yellowing)
Recommended Crops Citrus, grapes, corn, rice Soybeans, cereals, fruits
Solubility Fully soluble Fully soluble
Use Modes Foliar, fertigation, feed Foliar, fertigation, feed

11. Why Choose Chibio Biotech’s EDTA Chelates?

Consistent High Assay – Zn 14.6%, Mn 12.6%
Excellent Water Solubility & pH Compatibility
Low Impurities – <0.05% Insolubles
Bulk Ready & OEM Packaging Support
Suitable for Fertilizer, Feed, and Agricultural Applications


12. Why Use These Chelates in Your Business?

🌾 Precision Agriculture Ready – Ideal for high-value crops & fertigation systems
💧 Stable Chelated Form Prevents Precipitation – Ensures micronutrient availability
📦 Low Dosage, High Efficiency – Effective even in trace quantities
📈 Improve Crop Yield & Quality – Supports sustainable, balanced nutrition strategies
🌱 Custom Formulations Possible – Chibio supports tailored blends with other micronutrients


📩 Contact Us to Request Technical Documents or Samples

Looking to enhance your micronutrient portfolio or build a custom agricultural solution?

📧 Email: sales@chibiotech.com
📞 Phone: +86 532 66983270
🌐 Website: www.chibiotech.com
Partner with Chibio Biotech – Innovating with precision chelated micronutrients!

Get in touch with us to boost your business

Headquarter

Block B, Vanke Center, No.2 Heilongjiang South Road, Shibei District, Qingdao City, China 266033

Phone

+86 (0)532 66983270

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+86 156 6577 2296
+86 133 8100 5417

sales@chibiotech.com

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