D-biotin is water-soluble vitamin, which belongs to the B-complex group of vitamins. It generally serves as a covalently-bound coenzyme for several carboxylases. It is an essential micronutrient required for normal cell functions and can be obtained from both dietary sources as well as gut microbiota.
D-Biotin is a water-soluble B vitamin, also called vitamin B7 and formerly known as vitamin H or coenzyme R.
Biotin deficiency can be caused by inadequate dietary intake or inheritance of one or more inborn genetic disorders that affect biotin metabolism. Subclinical deficiency can cause mild symptoms, such as hair thinning or skin rash typically on the face. Neonatal screening for biotinidase deficiency began in the United States in 1984, with many countries testing for this disorder at birth. Individuals born prior to 1984 are unlikely to have been screened, obscuring the true prevalence of the disorder.
D-Biotin is an important component of enzymes involved in metabolizing fats and carbohydrates, influencing cell growth, and affecting amino acids involved in protein synthesis. Biotin assists in various metabolic reactions involving the transfer of carbon dioxide. It may also be helpful in maintaining a steady blood sugar level. Biotin is often recommended as a dietary supplement for strengthening hair and nails, though scientific data supporting these outcomes are weak. Nevertheless, biotin is found in many cosmetics and health products for the hair and skin.
Specification of D-Biotin
TEST ITEMS |
SPECIFICATION |
APPEARANCE |
White or almost white powder or granule |
Identification |
Positive |
Appearance of solution |
Colorless,Transparent |
Specific rotation |
+89–+93 |
Loss on drying |
≤1.0% |
Residue of ignition |
≤0.1% |
Assay of D-Biotin |
98%-100.5% |
Pb |
≤2 mg/kg |
As |
≤1mg/kg |
Applications & Benefits of D-Biotin
Biotin is water-soluble, which means the body doesn’t store it. It has many important functions in the body.
It’s necessary for the function of several enzymes known as carboxylases. These biotin-containing enzymes participate in important metabolic pathways, such as the production of glucose and fatty acids.
Biotin has a range of possible benefits in Health and beauty.
Summary: Many foods contain significant amounts of biotin, and it is also available as a supplement. Your gut bacteria can also produce it.
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