Aspergillus Niger Chitosan Hydrochloride

Aspergillus Niger Chitosan Hydrochloride

Additional information

Product Name

Water-soluble Aspergillus Niger Chitosan Hydrochloride

Form

Off-white to light yellow powder

Source

Aspergillus Niger (Corncob Fermentation)

Cas No.

70694-72-3

Specification

Water-soluble, viscosity 20-400cps (typical 20cps)

Main Applications

Cosmetics (skincare, haircare), Food, Wine, Pharma etc

Product Details

Aspergillus Niger Chitosan Hydrochloride – Premium Quality from Chibio Biotech

What is Aspergillus Niger Chitosan Hydrochloride?
Aspergillus Niger Chitosan Hydrochloride is a specialized, water-soluble derivative of chitosan obtained from the fungal species Aspergillus niger.

This chitosan variant is formed by the reaction of chitosan with hydrochloric acid, enhancing its solubility and making it highly versatile for various applications, particularly in pharmaceuticals, cosmetics, and food industries. It is a vegan, non-allergenic alternative to traditional chitosan derived from crustaceans.

CAS Number:

  • CAS No.: 70694-72-3

Chemical Structure:

  • Chemical Formula: (C6H11NO4)n⋅HCl(C_6H_{11}NO_4)_n · HCl
  • The chemical structure of Aspergillus Niger Chitosan Hydrochloride includes a backbone of D-glucosamine units linked by β-(1→4) glycosidic bonds, with hydrochloride groups (HCl)(HCl) attached. This modification significantly improves water solubility.

The repeating unit is represented as:

  • [–(C_8H_{15}NO_5)–NH_2·HCl–]n

Where:

  • NH_2 represents the amino groups in chitosan that are protonated by hydrochloric acid.
  • “n” indicates the degree of polymerization.

Specification

  • Appearance: Off-white to light yellow powder
  • Degree of Deacetylation: ≥ 85% (typically ≥98%)
  • Molecular Weight: 20,000 – 580,000 Da
  • Viscosity: 20-400 mPa.s (customizable) (typically 20cps, 100cps, 200cps, 400cps)
  • Moisture Content: ≤ 10%
  • Ash Content: ≤ 1.5%
  • Solubility: Highly soluble in water

This table illustrates a direct correlation between the viscosity and molecular weight of chitosan, where higher molecular weights result in increased viscosity.

This relationship is crucial for selecting the appropriate chitosan grade for various applications, as higher viscosity chitosan, due to its larger molecular structure, is ideal for creating thicker gels and films.

Additionally, the degree of deacetylation influences this relationship, further refining the material’s suitability for specific industrial uses.

Solubility

Chitosan Hydrochloride from Aspergillus niger is readily soluble in water, with ratio 1% (1g dissolved in 99ml water), even at neutral pH, making it suitable for a wide range of formulations and applications.

Kindly watch the videos of solubility of different types of vegetal chitosan: https://www.chibiotech.com/video/

Specification Customized Service

We offer tailored solutions to adjust the molecular weight, degree of deacetylation, and other specifications to meet your unique needs, ensuring optimal performance in your specific application.

Advantages & Benefits

  • Enhanced Water Solubility: Perfect for applications requiring a fully water-soluble biopolymer.
  • Vegan and Non-Allergenic: Ideal for individuals with shellfish allergies or those following a vegan lifestyle.
  • High Purity: Guarantees a clean, consistent product free from animal derivatives.
  • Biocompatible: Suitable for use in medical, pharmaceutical, and cosmetic formulations.

Functions

  • Film Formation: Forms strong, flexible films ideal for coatings and packaging applications.
  • Antimicrobial Activity: Effectively inhibits bacterial and fungal growth, making it suitable for use in preservatives and wound care.
  • Biodegradability: Environmentally friendly, decomposing naturally without causing harm to ecosystems.
  • Thickening Agent: Acts as a natural thickener and stabilizer in food, cosmetic, and pharmaceutical products.

Main Applications (More about applications)

  • *Cosmetics: Used in lotions, creams, and gels for its water-soluble, film-forming, and moisturizing properties.  (*Most Applications*)
  • Food & Beverage: Acts as a natural thickener and stabilizer in water-based products.
  • Pharmaceuticals: Key ingredient in drug delivery systems and wound care products due to its water solubility and biocompatibility.
  • Agriculture: Serves as a bio-stimulant and natural pesticide, improving plant health.
  • Water Treatment: Efficiently purifies water through coagulation and flocculation processes.
  • Wine Fining Agent: Enhances clarity and stability in wine by removing sediments and impurities.
  • Dietary Supplements: Offers health benefits as a water-soluble ingredient in various supplement formulations.

Flowchart

The production process of Aspergillus Niger Chitosan Hydrochloride includes the preparation of chitosan, reaction with hydrochloric acid, followed by purification, drying, sieving, and rigorous quality testing

The flowchart of aspergillus niger chitosan outlines the process for extracting chitosan from Aspergillus niger, a type of fungus. Here’s a step-by-step summary of the key points:

  1. Starting Material: Aspergillus niger is cultured through a fermentation process using corn.
  2. Extraction:
    • The fungal biomass undergoes a bulk flocculation.
    • This is followed by centrifugation to separate the components.
    • The pH of the resulting material is adjusted to alkaline conditions (pH 8-10).
    • Another round of centrifugation and isolation occurs.
    • The pH is adjusted back to neutral (pH 7), and the sediment is washed and precipitated.
    • The sediment is then extracted with 5% acetic acid at 100°C for five hours to get the clear solution.
    • It is washed again to achieve a clear solution with a neutral pH.
  3. Chitin Production:
    • The clear solution is treated with 7% sodium hydroxide (NaOH) at a ratio of 1:10 (W/V) at 50°C for three hours.
    • Centrifugal washing follows, resulting in the production of chitin as a clear solution to get the sediment.
  4. Deacetylation:
    • The sediment undergoes the deacetylation process. It’s treated with 20% NaOH at a ratio of 1:10 (W/V) and heated in a microwave at 480W for 15 minutes.
    • This step is crucial to convert chitin into chitosan by removing acetyl groups.
  5. Final Steps:
    • The final sediment, which is now deacetylated chitin or chitosan, is extracted.
    • It undergoes drying, followed by sieving to achieve the desired particle size.
  6. End Product: The final product is solid Aspergillus niger chitosan.

This process includes several steps involving pH adjustment, centrifugation, chemical treatments, and heating, which are critical to ensuring the purity and quality of the chitosan extracted from Aspergillus niger.

Here are simplified descriptions of the flowcharts for Chitosan Hydrochloride:

Chitosan Hydrochloride Production:

  • Step 1: Chitosan is mixed with water and hydrochloric acid.
  • Step 2: The solution is formed, and natural ethanol is added.
  • Step 3: Precipitation occurs, followed by centrifugal separation.
  • Step 4: The product is washed, followed by another round of ethanol addition.
  • Step 5: The mixture undergoes centrifugal separation, drying, sieving, and final testing.
  • Result: Chitosan Hydrochloride.

 

Why Choose Us? (More about us)

  • Expertise: Chibio Biotech brings over 8 years of experience in producing high-quality fungal-derived chitosan.
  • Certified Quality: Our products are ISO 22000:2018, Halal, Kosher, and Organic certified, ensuring compliance with the highest industry standards.  (>>See more about our certificates)
  • Customized Solutions: We offer bespoke chitosan solutions tailored to your specific needs, ensuring optimal performance.
  • Global Reach: Serving customers in over 50 countries, we have the expertise and capacity to support your business worldwide.

Why your businesses consider using vegetal chitosan?

Using vegetal chitosan in your applications or formulations offers significant benefits to businesses, as outlined below:

  1. Eco-Friendly and Sustainable: Vegetal chitosan is derived from plant sources such as mushrooms and fungi, making it an environmentally sustainable alternative to traditional animal-based chitosan. This aligns with growing consumer demand for green and eco-friendly products​​.
  2. Non-Allergenic and Vegan-Friendly: Unlike crustacean-derived chitosan, vegetal chitosan does not trigger shellfish allergies and is suitable for vegan and vegetarian consumers. This widens the market reach for products formulated with vegetal chitosan​.
  3. Versatility and Superior Functionality: Vegetal chitosan offers excellent biocompatibility, biodegradability, and antimicrobial properties. These attributes enhance its utility across various industries, including food, pharmaceuticals, cosmetics, textiles, and agriculture​​​.
  4. Enhanced Product Performance: In many applications, vegetal chitosan improves product qualities such as moisture retention, antimicrobial efficacy, and barrier properties. This leads to better-performing end products, such as longer shelf-life for food items or improved durability and functionality in textiles​​.
  5. Market Differentiation: Incorporating vegetal chitosan allows companies to differentiate their products by promoting natural, sustainable, and allergen-free claims, which are increasingly valued by health-conscious and environmentally aware consumers​​.

In summary, using vegetal chitosan can help your businesses enhance their product offerings, meet consumer demands for sustainable and non-allergenic ingredients, and improve your overall market positioning.

 

Explore the potential of Water-soluble Aspergillus Niger Chitosan Hydrochloride today! Contact us for more details and to request a custom quote. Let’s work together to bring nature’s best to your products.

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