Aspergillus Niger Chitosan High Density

Aspergillus Niger Chitosan High Density

Additional information

Product Name

Aspergillus Niger Chitosan High Density

Form

Off-white to light yellow powder

Source

Aspergillus Niger (Corncob Fermentation)

Cas No.

9012-76-4

Specification

Acid-soluble, Density ≥0.7g/ml

Main Application

Dietary Supplement for Fat Binder, Wine Fining Agent, Food, Cosmetics, etc

Product Details

Aspergillus Niger Chitosan High Density (Acid-Soluble, Density ≥0.7g/ml) – Premium Quality from Chibio Biotech

What is Aspergillus Niger Chitosan High Density?
Aspergillus Niger Chitosan High Density is a specially formulated, acid-soluble chitosan derived from the fungal species Aspergillus niger.

Characterized by its high density (≥0.7g/ml), this chitosan variant is optimized for applications requiring a more concentrated and compact form of chitosan, ensuring efficient use in various industries.

It is particularly suited for pharmaceutical,  specifically dietary supplement for fat binder with weight management function, cosmetic, and food applications where high density and solubility are essential.

CAS Number:

  • CAS No.: 9012-76-4 (general chitosan CAS number; specific CAS for fungal chitosan might vary)

Chemical Structure:

  • Chemical Formula: (C6H11NO4)n(C_6H_{11}NO_4)_n
  • The chemical structure of Aspergillus Niger Chitosan consists of D-glucosamine units linked by β-(1→4) glycosidic bonds, with an optimized structure to achieve higher density and excellent acid solubility.

The repeating unit can be represented as:

  • [–(C_8H_{15}NO_5)–]n

Where “n” represents the degree of polymerization.

Specifications for Acid-Soluble Aspergillus Niger Chitosan (High Density):

Specification Value
Degree of Deacetylation ≥ 98%
Appearance Off-white to light yellow powder
Odor and Taste Characteristic
pH 7.0 – 8.0
Viscosity (1% in 1% acetic acid) 15-20 cps
Mesh Size/Sieve Analysis 100% pass 80 mesh
Loss on Drying ≤ 8.0%
Total Ash ≤ 2.0%
Density ≥ 0.7 g/cm³
Heavy Metals
Arsenic (As) ≤ 2.0 ppm
Lead (Pb) ≤ 1.0 ppm
Cadmium (Cd) ≤ 0.5 ppm
Mercury (Hg) ≤ 0.5 ppm
Sum of Heavy Metals ≤ 20.0 ppm
Microbiological Quality
Total Plate Count < 1000 cfu/g
Yeast & Mold < 100 cfu/g
E. coli Negative
Salmonella Negative

 

Solubility

This high-density chitosan is fully soluble in dilute acidic solutions, typically at a 1% solubility ratio, making it easy to integrate into various formulations, especially where a concentrated chitosan solution is required.

Kindly watch the videos of solubility of different types of vegetal chitosan: https://www.chibiotech.com/video/

Specification Customized Service
At Chibio, We offer customized Aspergillus Niger Chitosan solutions to meet your specific needs, including adjustments to molecular weight, degree of deacetylation, and other properties, ensuring optimal performance for your intended application.

Advantages & Benefits

  • High Density: Provides a more compact form, enabling higher concentrations and efficient usage in formulations.
  • Enhanced Solubility: Fully soluble in acidic solutions, ideal for a wide range of applications.
  • Vegan and Non-Allergenic: Sourced from fungi, suitable for individuals with dietary restrictions or shellfish allergies.
  • High Purity: Ensures a clean, consistent product free from animal derivatives.
  • Biocompatible: Suitable for use in medical, pharmaceutical, and cosmetic formulations.

Functions

  • Film Formation: Forms strong, flexible films ideal for coatings, packaging, and drug delivery systems.
  • Thickening Agent: Acts as a natural thickener and stabilizer in food, cosmetic, and pharmaceutical products.
  • Antimicrobial Properties: Inhibits bacterial and fungal growth, enhancing product safety and longevity.
  • Bioactive Carrier: Ideal for delivering active ingredients in pharmaceuticals and cosmetics.

Main Applications (More about applications)

  • Dietary Supplement for Fat Binder: Acts as a fat binder in dietary supplements, aiding in weight management.
  • Wine Fining Agent: Enhances clarity and stability in wine by removing sediments and impurities, improving the overall quality.
  • Blood Cholesterol Reduction: Supports the reduction of blood cholesterol levels when used in dietary supplements.
  • Bandages and Sponges: Utilized in medical bandages and sponges for its excellent biocompatibility and wound healing properties.
  • Dental Health: Incorporated in dental care products for its antimicrobial properties and ability to improve oral hygiene.
  • Pharmaceuticals: Used in drug delivery systems and as a stabilizer in various formulations.
  • Cosmetics: Enhances moisturization and provides skin protection in lotions, creams, and gels.

Flowchart
The production process of Aspergillus Niger Chitosan High Density involves carefully controlled steps to ensure high density and optimal solubility, followed by rigorous testing to meet the highest quality standards.

The flowchart of aspergillus niger chitosan outlines the process for extracting chitosan from Aspergillus niger, a type of fungus. Here’s a step-by-step summary of the key points:

  1. Starting Material: Aspergillus niger is cultured through a fermentation process using corn.
  2. Extraction:
    • The fungal biomass undergoes a bulk flocculation.
    • This is followed by centrifugation to separate the components.
    • The pH of the resulting material is adjusted to alkaline conditions (pH 8-10).
    • Another round of centrifugation and isolation occurs.
    • The pH is adjusted back to neutral (pH 7), and the sediment is washed and precipitated.
    • The sediment is then extracted with 5% acetic acid at 100°C for five hours to get the clear solution.
    • It is washed again to achieve a clear solution with a neutral pH.
  3. Chitin Production:
    • The clear solution is treated with 7% sodium hydroxide (NaOH) at a ratio of 1:10 (W/V) at 50°C for three hours.
    • Centrifugal washing follows, resulting in the production of chitin as a clear solution to get the sediment.
  4. Deacetylation:
    • The sediment undergoes the deacetylation process. It’s treated with 20% NaOH at a ratio of 1:10 (W/V) and heated in a microwave at 480W for 15 minutes.
    • This step is crucial to convert chitin into chitosan by removing acetyl groups.
  5. Final Steps:
    • The final sediment, which is now deacetylated chitin or chitosan, is extracted.
    • It undergoes drying, followed by sieving to achieve the desired particle size.
  6. End Product: The final product is solid Aspergillus niger chitosan.

This process includes several steps involving pH adjustment, centrifugation, chemical treatments, and heating, which are critical to ensuring the purity and quality of the chitosan extracted from Aspergillus niger.

Simplified description of the flowchart for High Density Chitosan production:

  1. Chitosan: Start with the raw chitosan material.
  2. Washing: The chitosan undergoes an initial washing process to remove impurities.
  3. Drying: The washed chitosan is dried to remove excess moisture.
  4. Dissolving: The dried chitosan is then dissolved in a suitable solution.
  5. Filtering: The solution is filtered to remove any undissolved particles or impurities.
  6. Flocculating: A flocculation process is used to gather the chitosan particles together.
  7. Deleting Salt: Salts are removed from the flocculated chitosan to increase purity.
  8. Washing: The chitosan undergoes another washing step to remove any residual salts.
  9. Filtering: The solution is filtered again to ensure purity.
  10. Drying: The filtered chitosan is dried to achieve the desired moisture content.
  11. Smashing: Finally, the dried chitosan is smashed into a fine powder to achieve high density.

The final product is High Density Chitosan, ready for use in various applications.

Why Choose Us? (More about us)

  • Expertise: With over 8 years of experience, Chibio Biotech is a trusted leader in producing high-quality vegetal chitosan, including fungal-derived varieties.
  • Certified Quality: Our products are ISO 22000:2018, Halal, Kosher, and Organic certified, ensuring adherence to the highest industry standards.  (>>See more about our certificates)
  • Customized Solutions: We offer tailored chitosan solutions to meet your specific needs, ensuring the best performance for your applications.
  • Global Reach: Serving customers in over 50 countries, we have the expertise and capacity to support your business wherever you are.

Why your businesses consider using vegetal chitosan?

Using vegetal chitosan in your applications or formulations offers significant benefits to businesses, as outlined below:

  1. Eco-Friendly and Sustainable: Vegetal chitosan is derived from plant sources such as mushrooms and fungi, making it an environmentally sustainable alternative to traditional animal-based chitosan. This aligns with growing consumer demand for green and eco-friendly products​​.
  2. Non-Allergenic and Vegan-Friendly: Unlike crustacean-derived chitosan, vegetal chitosan does not trigger shellfish allergies and is suitable for vegan and vegetarian consumers. This widens the market reach for products formulated with vegetal chitosan​.
  3. Versatility and Superior Functionality: Vegetal chitosan offers excellent biocompatibility, biodegradability, and antimicrobial properties. These attributes enhance its utility across various industries, including food, pharmaceuticals, cosmetics, textiles, and agriculture​​​.
  4. Enhanced Product Performance: In many applications, vegetal chitosan improves product qualities such as moisture retention, antimicrobial efficacy, and barrier properties. This leads to better-performing end products, such as longer shelf-life for food items or improved durability and functionality in textiles​​.
  5. Market Differentiation: Incorporating vegetal chitosan allows companies to differentiate their products by promoting natural, sustainable, and allergen-free claims, which are increasingly valued by health-conscious and environmentally aware consumers​​.

In summary, using vegetal chitosan can help your businesses enhance their product offerings, meet consumer demands for sustainable and non-allergenic ingredients, and improve your overall market positioning.

Discover the benefits of Aspergillus Niger Chitosan High Density today! Contact us for more details or to request COA and a custom quote.

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