Allantoin: The Ultimate Natural Ingredient for Your Business

What is Allantoin?

Allantoin is a skin-soothing, healing, and moisturizing compound that is widely used in the cosmetic, pharmaceutical, and personal care industries.

Although allantoin can be found in nature botanical extracts of the comfrey plant,  the version we provide is synthetically produced, ensuring high purity and quality. This synthetic allantoin offers the same remarkable benefits as its natural counterpart and is a trusted choice for various applications, especially in skincare and wound care products.

Allantoin is a moisturizing, healing, anti-irritating, soothing, keratolytic and non-toxic chemical compound useful in cosmetic, dermatological and veterinary preparation.

It is an effective cell-proliferating and healing agent that stimulates good tissue formation.

It has an attested skin softening and keratolytic action, and also performs as a chemical cleaner of scaling and necrotic tissue.

CAS No and Chemical Structure

• CAS Number: 97-59-6
• Chemical Structure: Allantoin has the molecular formula C₄H₆N₄O₃, featuring a unique blend of urea and glyoxylic acid.

Solubility

Our synthetic allantoin is soluble in water and glycerin but has limited solubility in alcohols. This water-solubility makes it easy to incorporate into a range of formulations, from skincare creams to oral care products.

Benefits and Functions of Allantoin

1. Skin Soothing and Healing: Synthetic allantoin effectively soothes irritated skin and promotes wound healing, making it perfect for sensitive or damaged skin formulations.
2. Moisturizing: It acts as a humectant, drawing moisture into the skin, keeping it hydrated, soft, and smooth.
3. Cell Regeneration: Allantoin stimulates cell proliferation, aiding faster healing and skin rejuvenation.
4. Anti-Irritant Properties: It reduces inflammation and minimizes redness, ideal for sensitive skin formulations.
5. Exfoliating: Allantoin promotes natural exfoliation by gently removing dead skin cells, leaving the skin radiant and refreshed.

Specifications of Synthetic Allantoin

Main Applications

Allantoin is also a known keratoyltic, which means that it is able to increase the water held inside of your skin’s cells while also helping the desquamation process in the skin’s outer layers. In this sense, allantoin calms down irritations, helps shed the upper layers of dead skin cells and promotes the growth of healthy tissue.

Plus, it offers countless other benefits that may make it effective at treating eczema, psoriasis, burns and other skin conditions. It is particularly effective at smoothening the skin and is remarkable at helping speed up the healing of wounds.

Allantoin is suitable for any personal care application. Its use notably increases the performance of every cosmetic preparation:

• Used at low levels on intact skin gives a smooth and healthy appearance;
• Used on irritated, chapped and cracked skin provide relief from pain and promote healing.

1. Skincare Products: Used in creams, lotions, and serums for its moisturizing and healing properties.
2. Hair Care: Found in shampoos, tonics and conditioners to soothe the scalp and improve hair texture.
3. Oral Care: Incorporated in toothpaste and mouthwashes for its anti-irritant properties.
4. Pharmaceuticals: Utilized in topical medications for treating wounds, burns, and skin ulcers.
5. Cosmetics: Present in makeup products to provide skin protection and hydration.

6. Personal care products contains Allantoin as active ingredient: 

   • Body and face care: tonics, gels, creams, lotions, wipes.
   • Hand-care: gels, lotions, creams.
   • Shaving-care: shaving soaps, aftershaves, gels, lotions, creams.
   • Baby-care: diaper rash, bath products, gels, lotions, creams, powders, wipes.
   • Lips-care: sticks, creams.
   • Sun-care: sunscreens, after suns, suntans, gels, lotions, creams.
   • Bath products: shower gels, bubble baths, intimate, powders, wipes.

Quite a lot of research has been carried out on the compounds found in Allantoin.

• Hydrating: Increases the water content of skin.
• Desquamating: It encourages natural exfoliation in the stratum corneum, the outer layer of the skin.
• Repairing: It is well known for its ability to stimulate cell proliferation, encouraging new tissue growth.
• It is known to be extremely wound healing, research has shown that it clears away necrotic tissue, making way for a healthy new tissue.
• Healing: An active skin protector, it naturally encourages the skins healing process; making it a suitable ingredient for treating minor wounds and irritations.
• Relieves dryness: Promotes cellular regeneration, counteracting dryness and repairing an impaired barrier, allantoin encourages sensitive skin to become more resilient.
• Protecting: This is one ingredient that really does soften the skin, it also protects chapped, sun damaged skin, studies have shown that it protects against UV induced cell damage.
• Soothing: It is considered an excellent anti-irritant, calming and soothing inflamed skin. So its great when used in baby products.
• Free Radical Activity: Topical application helps reduce free radical activity on the skin.
• Keratolytic action: In performing its protective and regulatory functions, the outer layer of skin our epidermis, synthesises a very large number of proteins and oils (lipids) that are naturally found in the stratum corneum.

Production Flowchart

1. Synthesis: Allantoin is synthetically produced using controlled chemical processes.
2. Purification: The synthesized product undergoes a series of purification processes to ensure high purity.
3. Filtration: It is filtered to remove impurities.
4. Drying and Packaging: The final product is dried, powdered, and packed for distribution.

How Does Allantoin Work?

Synthetic allantoin promotes cell proliferation, aiding in tissue repair and wound healing. It soothes irritated skin, reduces inflammation, and forms a protective barrier to lock in moisture, enhancing skin elasticity and hydration. It also gently exfoliates dead skin cells, leaving the skin smooth and radiant.

Dosage Guideline

The typical use of allantoin is between 0.1-0.5%, but may be increased up to 2%. Allantoin can be easily dissolved in aqueous formulations at room temperature up to 0.5%. It can be incorporated in emulsions at 0.5-2% with temperature over 50°C.

• Skincare Products: 0.1% to 2% concentration
• Hair Care Products: 0.1% to 0.5%
• Oral Care Products: Up to 0.5%
• Pharmaceutical Products: Dosage varies according to the application and prescription.

Why Choose Chibio Biotech?

Qingdao Chibio Biotech Co., Ltd. is a leading manufacturer of high-quality synthetic allantoin and other natural ingredients. Here’s why Chibio Biotech stands out:

1. Quality Assurance: With certifications like ISO22000: 2018, Kosher, Halal, and FDA approvals, Chibio Biotech guarantees the highest quality of synthetic allantoin.
2. Innovative Production: Using advanced technology and equipment, Chibio Biotech ensures consistent quality and purity in every batch.
3. Experienced Team: Over 8+ years of experience in manufacturing natural ingredients, with a dedicated R&D team.
4. Global Reach: Trusted by customers in over 50 countries across North America, Europe, Asia, and beyond​.

Why Use Synthetic Allantoin in Your Business?

1. Versatility: Suitable for various applications, from cosmetics to pharmaceuticals.
2. Effective Results: Proven benefits for skin healing, moisturizing, and cell regeneration.
3. High Purity: Our synthetic allantoin ensures a consistent, high-quality product every time.
4. Enhanced Product Performance: Incorporating synthetic allantoin can significantly improve product efficacy, attracting more customers.

Incorporate Allantoin Today! By integrating our synthetic allantoin into your products, you’ll experience the benefits of this remarkable ingredient, ensuring customer satisfaction and loyalty.

Contact Chibio Biotech now to source premium quality synthetic allantoin for your business and unlock the potential of this powerful skincare solution​.