Discover the Power of Modified Citrus Pectin (MCP), a multifunctional natural ingredient with huge market potential

What is Modified Citrus Pectin (MCP)?

Modified Citrus Pectin (MCP) is a scientifically enhanced natural ingredient derived from citrus fruit peels. Unlike regular pectin, MCP undergoes a unique modification process to improve its solubility and absorption in the body, unlocking an array of health benefits. This bioavailable form of pectin is widely recognized for its applications in functional foods, dietary supplements, cosmetics, and medicines.

The full name of small molecule pectin is Modified Citrus Pectin (MCP), also known as Low Molecular Citrus Pectin (LCP). It is a polysaccharide complex with galactose as the main component extracted from the peel and pulp of citrus, lemon, orange, and grapefruit.

MCP has multiple pharmacological effects such as anti-tumor, anti-aging, anti-virus, anti-inflammatory, anti-ulcer, hypoglycemic, hypolipidemic, anti-coagulation and immune function enhancement, and has attracted more and more attention.

Source

MCP is derived from citrus fruit peels, primarily oranges and grapefruits. Its natural origin ensures safety, sustainability, and suitability for a variety of applications.

Comparison between MCP & CP:

• CP (Citrus Pectin): A substance used as a thickener, emulsifier, and stabilizer.
• MCP (Modified Citrus Pectin): A functional ingredient derived from citrus pectin.
• Comparison Between CP and MCP:
  • MCP has a lower molecular weight and degree of esterification compared to CP.
  • MCP is bioavailable and absorbs into the bloodstream, while CP primarily acts in the gastrointestinal tract.

MCP vs CP Comparison
Property	MCP (Modified Citrus Pectin)	CP (Citrus Pectin)
Introduction	A functional ingredient derived from citrus pectin.	A substance used as a thickener, emulsifier, and stabilizer
Molecular Weight	5,000-22,000 Da	50,000-300,000 Da
Degree of Esterification	2-33%	40-78%
Site of Action	Absorbed into bloodstream	Acts only in the gastrointestinal tract
Applications	Functional foods, health ingredients, special medical applications, cosmetics	Food additive (thickener, emulsifier, stabilizer)

CAS Number and Chemical Structure

• CAS Number: 9035-41-2
• Chemical Structure: MCP consists of short-chain polysaccharides rich in galacturonic acid residues, partially esterified with methoxy groups. This modified structure improves water solubility and bioactivity.

Specifications

• Appearance: Light yellow to brown powder
• Solubility: Highly soluble in water, 15% solubility degree
• Molecular Weight: 5,000 ~ 22,000 Da (depending on the degree of modification)
• Main ingredients of MCP: water-soluble fiber polysaccharide rich in galactose, the main component of which is galacturonic acid ≥ 85%

Items	Specifications
Appearance	Light yellow to brown powder, Loose granular, uniform particle size
Taste & Odor	Characteristics
Moisture	≤12%
Galacturonic Acid	≥85%
Degree of Esterification	2-33
Molecular Weight	5,000 ~ 22,000 Da
Heavy Metals   Pb	≤1.0 ppm
Transmittance	89.7 1% solution, spectrophotometer
Viscosity	According to the request (4% solution, viscometer)
Micorobiological   Total Plate Count   Mold   Coliform Group   Salmonella   Staphylococus Aureus	≤1000 cfu/g ≤50 cfu/g ≤30 cfu/g Negative Negative

Solubility

MCP is highly soluble in water  and compatible with most food, beverage, and supplement formulations. Its fine powder form ensures ease of mixing without clumping.

Key Health Benefits of MCP

1. Cancer Support and Prevention

MCP binds to Galectin-3, a protein associated with tumor growth and metastasis. By inhibiting Galectin-3, MCP disrupts pathways that fuel cancer progression, particularly in prostate and breast cancers. Early studies also suggest MCP may enhance sensitivity to chemotherapy, reduce toxic side effects, and slow cancer progression markers like PSA levels in prostate cancer.

2. Heavy Metal Detoxification

MCP is a natural chelator that supports the removal of toxic heavy metals, including lead, cadmium, and arsenic, without depleting essential minerals such as zinc, copper, and iron. This selective detoxification promotes a cleaner internal environment and overall wellness.

3. Blood Sugar and Lipid Regulation

MCP helps maintain healthy blood sugar and cholesterol levels by delaying intestinal absorption of sugars and fats. It activates enzymes related to metabolism, supporting cardiovascular and kidney health while promoting balanced lipid profiles.

4. Immune System and Cellular Health

MCP enhances immune function, fostering healthy cellular growth and reducing inflammation. Its antioxidant properties protect cells from oxidative damage, a key factor in aging and chronic diseases.

5. Skin Health and Brightening

MCP forms a protective film on the skin, locking in moisture for deep hydration. It also reduces melanin production, brightens the complexion, and protects against UV damage, making it a valuable ingredient in premium skincare formulations.

6. Liver and Gastrointestinal Health

With its high water solubility, MCP forms a protective layer in the gastrointestinal tract, preventing alcohol absorption and supporting liver detoxification. Its fiber content enhances gut motility, relieves constipation, and promotes digestive health.

7. Functional and Versatile

From functional foods to pharmaceuticals, MCP is an adaptable ingredient suitable for a variety of products aimed at boosting health and well-being.

Functions

• Acts as a natural chelator of heavy metals (e.g., lead, mercury).
• Supports cardiovascular health by reducing cholesterol levels.
• Enhances nutrient absorption and bioavailability.
• Provides antioxidant properties for cellular protection.

Main Applications of Modified Citrus Pectin (MCP):

1. MCP for Cancer Therapy Support
   • Mechanism: MCP interacts with Galectin-3, inhibiting tumor growth, reducing metastasis risk, and enhancing immune cell activity.
   • Benefits: Reduces chemotherapy side effects, improves drug resistance, and supports therapy for tumors expressing high Galectin-3 levels.
   • Clinical Safety: Non-toxic to cells and shows no adverse side effects in clinical use.
2. MCP for Gut Health
   • Improves intestinal flora balance (promoting beneficial bacteria).
   • Aids in regulating constipation and diarrhea.
   • Supports over 90% fiber intake to stimulate gut motility.
3. MCP for Beauty and Wellness
   • Enhances skin hydration and anti-radiation properties.
   • Promotes cell repair, anti-aging effects, and scar fading.
   • Offers antibacterial properties and helps eliminate heavy metals.
4. MCP for Metabolic Health (Addressing Hypertension, High Blood Sugar, and High Cholesterol)
   • Slows intestinal absorption of fats and sugars.
   • Stimulates insulin production while inhibiting glucagon secretion.
   • Activates sugar-metabolizing enzymes.
   • Enhances cholesterol breakdown and excretion.
   • Exhibits anti-vascular disease properties through its low-molecular-weight structure.
5. MCP for Liver Protection
   • Acts as a dual-function agent for alcohol detoxification and liver protection:
     1. Forms a protective film in the gastrointestinal tract to prevent alcohol absorption, protecting the stomach and liver.
     2. Activates alcohol-decomposing enzymes to accelerate the breakdown of alcohol into water and carbon dioxide.
   • Demonstrated superior detoxification effects compared to traditional remedies like kudzu root.
6. MCP for Heavy Metal Detoxification
   • Selectively removes toxic heavy metals (lead, chromium, arsenic, mercury, cadmium) without affecting beneficial elements like calcium, magnesium, selenium, and zinc.
   • Mechanism: MCP’s polysaccharide chains form stable “egg-box” structures with heavy metals, allowing safe excretion through urine and feces.
   • Health Benefits:
     • Protects against neurological, cardiovascular, and skeletal damage caused by heavy metals.
     • Mitigates risks of cancer, DNA damage, and other severe health impacts, especially for vulnerable groups like children, pregnant women, and adults with chronic exposure.
7. MCP for Radiation Protection
   • Proven to reduce radioactive cesium (Cs-137) levels in affected populations.
   • Improves heart function and cardiovascular symptoms associated with radiation exposure.
   • Demonstrated effectiveness in post-nuclear accident scenarios, such as Chernobyl, by significantly lowering radioactive burdens in children.
8. MCP for Anti-Aging
   • Supports gut homeostasis by maintaining intestinal epithelial integrity and reducing oxidative stress (ROS).
   • Enhances autophagy and DNA repair mechanisms, promoting cellular renewal and extending lifespan.
   • Plays a crucial role in mitigating age-related diseases like cancer, Alzheimer’s, and cardiovascular disorders by balancing oxidative and anti-inflammatory responses.
9. MCP in the Dairy Industry
   • Advantages:
     • Strong functionality aligned with the trend of functional food innovation.
     • Excellent processing stability without altering the flavor or color of original products.
     • Long shelf life (over 5 years) under normal sealed conditions.
     • Recognized as a safe ingredient by FAO and WHO with no daily intake restrictions.
   • Applications:
     • Used in specialized medical foods, nutritional supplements, functional foods (immune boosting, lipid reduction, detoxification, and gut health).
     • Commonly applied in dairy products, beverages, gummies, biscuits, and jellies.
   • Stability:
     • MCP remains highly stable in acidic beverages.
     • Minor adjustments required to prevent fiber formation in neutral pH dairy products.
10. MCP as a Key Functional Nutritional Ingredient

• • MCP is a safe, effective, and versatile ingredient recognized for its unique health benefits.
  • Suitable for functional foods targeting specific health conditions, making it a prime choice for the growing nutraceutical and specialized nutrition market.

This shows MCP’s powerful functionality and wide-ranging applications in health and food industries, highlighting its cutting-edge role in addressing modern health challenges.

Production Flowchart

1. Raw Material Selection: Collection of high-quality citrus peels.
2. Extraction: Pectin extraction through an aqueous process.
3. Modification: Enzymatic or chemical modification to enhance bioactivity.
4. Purification: Removal of impurities and drying to produce a fine powder.
5. Quality Assurance: Rigorous testing to ensure compliance with safety and purity standards.

Why Choose MCP for Your Products?

1. Backed by Science: Supported by preliminary studies highlighting its potential in cancer care, detoxification, and metabolic health.
2. Sustainable and Natural: Derived from renewable citrus sources, making it eco-friendly and safe.
3. Broad Applications: Perfect for creating innovative solutions in dietary supplements, skincare, functional foods, and pharmaceuticals.
4. Consumer Appeal: Health-conscious consumers seek natural, proven ingredients like MCP to enhance their well-being.

Why Partner with Chibio Biotech?

Experience: With over 8 years of expertise in natural ingredient production, Chibio Biotech is a trusted leader in the field.
Innovation: We leverage advanced technology to ensure MCP’s bioavailability and effectiveness.
Customization: Tailored solutions to meet your specific needs, ensuring product excellence.
Sustainability: Committed to eco-friendly sourcing and manufacturing practices.

Contact Us

Interested in exploring the potential of Modified Citrus Pectin (MCP) for your products? Reach out to Chibio Biotech today to learn more and request samples. Transform your formulations with MCP, the natural choice for health, beauty, and wellness.