Agaricus Bisporus Chitosan – High-Quality Mushroom-Derived Chitosan

What is Agaricus Bisporus Chitosan?
Agaricus Bisporus Chitosan is a unique, plant-based chitosan derived from the white button mushroom (Agaricus bisporus).

This form of chitosan offers a sustainable, non-animal alternative to traditional chitosan sourced from crustaceans. With its excellent biocompatibility, biodegradability, and functional properties, Agaricus Bisporus Chitosan is ideal for various applications in pharmaceuticals, cosmetics, food, and other industries.

CAS Number:

• CAS No.: 9012-76-4 (common to most chitosan, specific to source if needed)

Chemical Structure:

• Chemical Formula: (C6H11NO4)n(C_6H_{11}NO_4)_n(C6​H11​NO4​)n​
• The chemical structure of Agaricus Bisporus Chitosan consists of D-glucosamine units linked by β-(1→4) glycosidic bonds. This structure imparts the characteristic properties of chitosan, such as its ability to form films, act as a thickener, and provide antimicrobial effects.

The repeating unit can be represented as:

• [–(C_8H_{15}NO_5)–]n

Where “n” represents the degree of polymerization.

Specification

We offer a wide range of grades and specifications for Agaricus Bisporus Chitosan to meet your specific requirements.

Whether you need a particular viscosity, degree of deacetylation, or solubility profile (acid-soluble or water-soluble), we can customize our product to align with your exact needs. Our technical team is ready to collaborate on tailored solutions that drive your business forward.

• Appearance: Off-white to light yellow powder
• Degree of Deacetylation: ≥ 90% (Typically ≥98%)
• Viscosity: 20cps-1000 cps(mPa.s)
• Molecular Weight: 20k-1500k Da
• Solubility: Soluble in acidic solutions  or water

Here below are the regular types of Agaricus Bisporus Chitosan:

• GBS001-003: Acid-soluble Agaricus Bisporus Chitosan with viscosity 20-1000 cps (mpa.s)
• GBS004: Water-soluble Agaricus Bisporus Chitosan Hydrochloride  (with viscosity 20 cps (mpa.s)/20kDa)
• GBS005: Water-soluble Agaricus Bisporus Chitosan Oligosaccharide (≤5Kda)
• GBS010: Water-soluble Agaricus Bisporus Chitosan Carboxymethyl (N,O-CMC)

This table illustrates a direct correlation between the viscosity and molecular weight of chitosan, where higher molecular weights result in increased viscosity.

This relationship is crucial for selecting the appropriate chitosan grade for various applications, as higher viscosity chitosan, due to its larger molecular structure, is ideal for creating thicker gels and films.

Additionally, the degree of deacetylation influences this relationship, further refining the material’s suitability for specific industrial uses

Solubility
Agaricus Bisporus Chitosan is soluble in dilute acidic or water solutions, typically at a 1% solubility ratio, which makes it versatile for use in various formulations, including cosmetics, pharmaceuticals, and food products.

Kindly watch the videos of solubility of different types of vegetal chitosan: https://www.chibiotech.com/video/

Specification Customized Service
We offer tailored solutions to adjust the molecular weight, degree of deacetylation, and other specifications to meet your specific application needs, ensuring optimal performance.

Advantages & Benefits

• Vegan and Non-Allergenic: Perfect for individuals with shellfish allergies or those following a vegan lifestyle, as it is derived from mushrooms.
• High Purity: Guarantees a clean, consistent product free from animal derivatives.
• Eco-Friendly: Produced sustainably, minimizing environmental impact.
• Biocompatible: Safe for use in medical, pharmaceutical, and cosmetic formulations.

Functions

• Antimicrobial Activity: Effectively inhibits bacterial and fungal growth, enhancing product safety and longevity.
• Film Formation: Forms strong, flexible films suitable for coatings, packaging, and drug delivery systems.
• Thickening Agent: Acts as a natural thickener and stabilizer in food, cosmetic, and pharmaceutical products.
• Biodegradability: Environmentally friendly, breaking down naturally without harming ecosystems.

Main Applications （More about applications)

• Pharmaceuticals: Utilized in drug delivery systems, stabilizers, and other pharmaceutical formulations due to its biocompatibility and high solubility.
• Cosmetics: Enhances skin moisturization, protection, and overall product stability in lotions, creams, and gels.
• Food: Acts as a natural thickener and stabilizer in various food products, improving texture and shelf-life.
• Wound Healing: Promotes faster and more effective healing of wounds due to its biocompatibility and antimicrobial properties.
• Tissue Regeneration: Supports tissue regeneration and repair, making it valuable in biomedical applications.

Flowchart
The production process of Agaricus Bisporus Chitosan involves carefully controlled steps, including extraction, purification, and modification, followed by rigorous testing to ensure the highest quality.

The flowchart of mushroom (oyster mushroom & agaricus bisporus) chitosan illustrates the process of producing chitosan and its derivatives from mushroom material. Here’s a summary of the key content:

1. Starting Material: The process begins with mushroom material as the source.
2. Filtration: The mushroom material undergoes a filtration process.
3. Protein Removal: Proteins are then removed from the filtered material using an alkali solution.
4. Ash Removal: Ash content is subsequently removed with acid.
5. Chitin Extraction:
   • Acid is added without bubbles to proceed to the next stage.
   • Chitin is extracted, which is not soluble in acid.
   • An acetylation step removes the acetyl groups from the chitin using sodium hydroxide (NaOH), converting it into chitosan, which is soluble in acid.
6. Drying: The acid-soluble chitosan is then dried to produce the final mushroom chitosan product, showcased as a white powder.
7. Chitosan Derivatives: Parallel to the drying process, there is a branch leading to the production of various chitosan derivatives:
   • Chitosan Hydrochloride: Chitosan converted into its hydrochloride form.
   • Enzyme Hydrolysis: Produces chitosan oligosaccharide through enzymatic hydrolysis.
   • Carboxymethyl Chitosan: Derived through the carboxymethylation of chitosan.

The flowchart depicts a methodical approach to converting mushroom material into various forms of chitosan, focusing on the purification and chemical modification steps necessary to achieve different chitosan-based products for use in various applications.